NOF CORPORATION’s latest products, COATSOME® SS-OP is now available.
We have newly developed COATSOME® SS-series lipids for effective instracellular delivery and lower toxicity. COATSOME® SS-series contains dual sensing motifs that can respond to the intracelluar environment; tertiary amines respond to an acidic compartment (endosamo/lysosome) for membrane destabilization, and disulfide bond that can cleave in reductive environment(cytoplasm). These two units synergize for efficient intracellular delivery of encapsulated drugs with enhanced biosafety.
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NOF AMERICA CORPORATION
Tel: NY Office: +1-914-681-9790 (Ext. 20)
CA Office: +1-949-253-5764
NOF EUROPE GmbH
[Asia/Oceania, Japan Region]
DDS Development Division