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2-arm Branched PEG (SUNBRIGHT® GL2 Series)

2-arm activated branched PEGs can introduce two PEG chains into pharmaceutical substances by a single linkage and improve the pharmacokinetic profile of the pharmaceutical substances efficiently *. 
2-arm activated branched PEGs have already been used in some marketed PEGylated drugs. 
* Yulia V. et al., Bioconjugate Chem., 23, 1452(2012). 

 








 

2arm branched PEG, -CONH(CH2)2-CHO, Mw 20,000


2arm branched PEG, -CONH(CH2)2-ONH2, Mw 20,000


2arm branched PEG, -(CH2)3NHCO(CH2)3COO-NHS, Mw 20,000


2arm branched PEG, -(CH23NHCO(CH2)2-MAL, Mw 20,000 /p>


2arm branched PEG, -COO-pNP, Mw 20,000


2arm branched PEG, -(CH2)3-NH2, Mw 20,000   


2arm branched PEG, -COO-NHS, Mw 20,000


2arm branched PEG, -CONH(CH2)2-CHO, Mw 40,000


2arm branched PEG, -CONH(CH2)2-ONH2, Mw 40,000


2arm branched PEG, -(CH2)3NHCO(CH2)3COO-NHS, Mw 40,000


2arm branched PEG, -(CH23NHCO(CH2)2-MAL, Mw 40,000


2arm branched PEG, -(CH23NHCO(CH2)5-MAL, Mw 40,000 *make-to-order