8. Poly-Hydroxyl Activated PEGS

NOF developed Poly-Hydroxyl activated PEG which has four hydroxyl groups as shown below.
SUNBRIGHT® XE Series has four such hydroxyl groups to increase its hydrophilicity.
By the high hydrophilc property, non-specific adsorption of proteins can be depressed compared with the conventional methoxy PEG.
Furthermore, even if the molecular weight of PEG is small, it can hold a much larger number of water molecules compared with methoxy PEG.