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3. PEG Phospholipids

PEG phospholipids can be applied to liposomal drug
formulations to prolong the half-life of plasma circulation in drugs. Coating of the liposomal surface with polyethylene glycol suppresses drug clearance in vivo by the reticuloendothelial system, thereby prolonging the half-life of the drug.
PEG-modified lipids can also be used as emulsifiers and stabilizers of microspheres in aqueous solutions.

 

p34_Figure_PEG Phospholipids

 

DPPE-PEG 5,000
N-(Carbonyl-methoxypolyethyleneglycol 2000)-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine, sodium salt [1g amber glass bottle]


DSPE-2arm PEG 2,000
N-[Carbonyl-2’,3’-Bis(methoxypolyethyleneglycol 2000)]-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt 


DSPE-2arm PEG 5,000
N-[Carbonyl-2’,3’-Bis(methoxypolyethyleneglycol 5000)]-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt [1g amber glass bottle]


DSPE-PEG 2,000
N-(Carbonyl-methoxypolyethyleneglycol 2000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt


DSPE-PEG 5,000
N-(Carbonyl-methoxypolyethyleneglycol 5000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt


DPPE-PEG 2,000
N-(Carbonyl-methoxypolyethyleneglycol 2000)-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine, sodium salt[1g amber glass bottle]


DMPE-PEG 2,000
N-(Carbonyl-methoxypolyethyleneglycol 2000)-1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine, sodium salt [1g amber glass bottle]


DSG-PEG 5,000
1,2-Distearoyl-rac-glycerol, methoxypolyethylene Glycol
[1g amber glass bottle or 10g aluminum pouch]


DSG-PEG 2,000
1,2-Distearoyl-rac-glycerol, methoxypolyethylene Glycol
[1g amber glass bottle or 10g aluminum pouch]


DPG-PEG 2,000
1,2-Dipalmitoyl-rac-glycerol, methoxypolyethylene Glycol
[1g amber glass bottle]


DOG-PEG 2,000
1,2-Dioleoyl-rac-glycerol, methoxypolyethylene Glycol


DMG-PEG 2,000
1,2-Dimyristoyl-rac-glycerol, methoxypolyethylene Glycol
[1g amber glass bottle]