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3. PEGylated Lipids

PEGylated lipids can be applied to liposomal drug formulations to prolong the plasma half-life of the drugs. Coating of the liposomal surface with polyethylene glycol would suppress the uptake of the drug by the reticuloendothelial system, thereby prolonging the half-life of the drug in the plasma. PEG-modified lipids can also be used as emulsifiers and stabilizers of microspheres in aqueous solutions.

 

DSPE-PEG 2,000
N-(Carbonyl-methoxypolyethyleneglycol 2000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt


DSPE-2arm PEG 2,000
N-[Carbonyl-2’,3’-Bis(methoxypolyethyleneglycol 2000)]-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt 


DSPE-PEG 5,000
N-(Carbonyl-methoxypolyethyleneglycol 5000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt


DSPE-2arm PEG 5,000
N-[Carbonyl-2’,3’-Bis(methoxypolyethyleneglycol 5000)]-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt [1g amber glass bottle]


DMG-PEG 2,000
1,2-Dimyristoyl-rac-glycerol, methoxypolyethylene Glycol
[1g amber glass bottle]


DMG-PEG 5,000
1,2-Dimyristoyl-rac-glycerol, methoxypolyethylene Glycol
[1g amber glass bottle]


DOG-PEG 2,000
1,2-Dioleoyl-rac-glycerol, methoxypolyethylene Glycol


DOG-PEG 5,000
1,2-Dioleoyl-rac-glycerol, methoxypolyethylene Glycol


DPG-PEG 2,000
1,2-Dipalmitoyl-rac-glycerol, methoxypolyethylene Glycol
[1g amber glass bottle]


DPG-PEG 5,000
1,2-Dipalmitoyl-rac-glycerol, methoxypolyethylene Glycol
[1g amber glass bottle]


DSG-PEG 2,000
1,2-Distearoyl-rac-glycerol, methoxypolyethylene Glycol
[1g amber glass bottle or 10g aluminum pouch]


DSG-PEG 5,000
1,2-Distearoyl-rac-glycerol, methoxypolyethylene Glycol
[1g amber glass bottle or 10g aluminum pouch]