Customized PEGylation of Biopharmaceuticals
PEGylation is an established tool to increase potency, half-life and solubility of biopharmaceuticals.
NOF / Celares offer customized PEGylation services for the development of PEGylated drugs.
For research and development of therapeutics
Advantage of working with us
PEGylation Feasibility Studies
PEGylation is an established delivery system for biopharmaceuticals, such as peptides, proteins, antibody fragments, aptamers, domains and other biologics. PEGylation can significantly improve the pharmacological and physicochemical properties of drugs.
NOF, together with our partner Celares, can support your PEG-drug development work at a reasonable timeline and cost.
If you are interested in our PEGylation service, please feel free to contact us.
Advantages of PEGylation
PEGylation technology can be used for modifying biological compounds such as cytokines, antibody fragment, interleukins, hormones, oligonucleotides and some of proteins and peptides.
PEGylation can be effective in :
- Improving Bioavailability
- Prolonging Blood Circulation
- Maximizing Pharmacokinetics
- Lowering Immunogenicity
- Decreasing Frequency of Dosing
NOF provides high-performance activated PEGs for PEGylated drugs from early development stage to commercial use. We have over 20 years of experience manufacturing high-quality methoxy polyethylene glycol, a key starting material of activated PEG in the pharmaceutical field. Our activated PEGs have a narrow polydisperity and a low diol content with a wide range of molecular weight, ranging from 2kDa to 80kDa.