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4. Branched PEGs

We provide 2 arm-, 3 arm- and 4 arm branched type- Activated PEGs. NOF supply various Activated PEGs possessing like maleimide, aldehyde, amine and activated NHS as the terminal functional groups. Although aqueous solutions of higher-molecular PEG derivatives tend to show increased viscosity, use of higher-branched Activated PEGs, such as 4-branched derivatives, is useful to reduce the viscosity of the relevant aqueous solutions, even without any change of the molecular weights. Collaborating with Enzon Pharmaceuticals, Inc., NOF has a right to sell their unique Lysine Branched PEG (SUNBRIGHT LY series) for customer research purpose only. Lysine Branched PEG has been already used in several marketed PEG-drugs such as PEGUSIS®, MACUGEN® and CIMZIA® for 10 years.

 

2arm branched PEG, -CONH(CH2)2-CHO, Mw 20,000 [100mg amber glass bottle]


2arm branched PEG, -CONH(CH2)2-ONH2, Mw 20,000 [100mg amber glass bottle]


2arm branched PEG, -(CH2)3NHCO(CH2)3COO-NHS, Mw 20,000 [100mg amber glass bottle]


2arm branched PEG, -(CH23NHCO(CH2)2-MAL, Mw 20,000 [100mg amber glass bottle]/p>


2arm branched PEG, -COO-pNP, Mw 20,000[100mg amber glass bottle]


2arm branched PEG, -(CH2)3-NH2, Mw 20,000   [100mg amber glass bottle]


2arm branched PEG, -COO-NHS, Mw 20,000 [100mg amber glass bottle]


2arm branched PEG, -CONH(CH2)2-CHO, Mw 40,000 [100mg amber glass bottle]


2arm branched PEG, -CONH(CH2)2-ONH2, Mw 40,000 [100mg amber glass bottle]


2arm branched PEG, -(CH2)3NHCO(CH2)3COO-NHS, Mw 40,000 [100mg amber glass bottle]


2arm branched PEG, -(CH23NHCO(CH2)2-MAL, Mw 40,000 [100mg amber glass bottle]


2arm branched PEG, -(CH23NHCO(CH2)5-MAL, Mw 40,000 [100mg amber glass bottle]