Ultra-Purity Polysorbate 80[HX2] and 20[GS]

Polysorbate 80 has been widely used as an emulsifier and solubilizer in pharmaceutical industry. NOF supplies ultra-pure Polysorbate 80(HX2)™ for injectable grade, which has outstanding features as follows;

  • Vegetable Source (No animal sources)
  • Ultra-pure Products
  • Low Impurities
  • Low Peroxide
  • Colorless and Odorless
  • High Stability
  • Low Allergic Reaction (Low Degranulation)
  • High Safety Features (Low Cell Toxicity & Hemolysis)
  • Multi-Compendial (NF (USP), EP and JP)


Polysorbate80(HX2)™, which meets NF (USP), EP and JP requirement is number one quality product in the world among Polysorbate80s.
Polysorbate80(HX2)™ can be used as emulsifier and solubilizer for peroxide sensitive drug to avoid oxidation or degradation of the drug because of low peroxide feature.

Additionally, because of high safety characteristic, concentration of Polysorbate80(HX2)™ can be increased for poorly water soluble drugs. In rat study, Polysorbate80(HX2)™ triggered less histamine release from rat mast cells compared to conventional Polysorbate80 formulations. The latest in-vivo dog study has also indicated less histamine release of Polysorbate80(HX2)™. The great feature of low allergy allows clients to use for drug formulations in safety.
For these outstanding characteristics of Polysorbate80(HX2)™ is recognized as worldwide standard product in pharmaceutical industry, especially for parenteral formulations.

Polysorbate 80 (HX2)


Polysorbate 20(GS)™
Polyoxyethylene Sorbitan Laurate

Polysorbate 20(GS) manufactured by NOF CORPORATION is a high-purity product of Polysorbate in the world with extremely low peroxide levels, which makes more stable of some biologic and/or small molecule in their formal formulations.

Polysorbate 20[GS]

Polyoxyethylene Sorbitan Laurate CAS NO.:9005-64-5Regulatory Status*1:JPE, EP, NF

Injectable grade. Ultra Purity Polysorbate 80, NF, EP, and JP (GMP) Package size: 100g, 1kg, 10kg