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Phospholipids and Lipids for Liposomal Formulations

Using the world's most advanced synthetic and purification technologies, NOF manufactures and supplies a series of highpurity lipid derivatives (COATSOME® Series) suitable for the formulation of lipid nanoparticles for nucleic acid and gene therapy drugs, liposomal and emulsion formulations for small molecule drugs.

Especially for the lipid nanoparticle formulation, We offer our proprietary ionizable lipids (COATSOME® SS Series) which enable efficient delivery of nucleic acids and low toxicity. In addition, we can respond to requests from our customers with tailor-made synthesis of any phospholipids with the desired structures.



cGMP Manufacturing Facility
Bulk phospholipids produced at our own validated facility under cGMP operation have been supplied worldwide for commercial drugs with long-standingreputations for quality and reliability for many years.
cGMP Manufacturing Facility

Drug Master Filings
NOF has already submitted more than 35 DMFs regarding various kinds of NOF manufactured phospholipids to the US FDA, so that customers can rely on our quality. We submit DMFs according to customers' requests and development needs.

Custom Synthesis
Custom synthetic phospholipids and lipids can be produced at customer's request.

N-(aminopropyl polyethyleneglycol)carbamyl-distearoylphosphatidyl-ethanolamine *make-to-order

DSPE-PEG 5,000
N-(Carbonyl-methoxypolyethyleneglycol 5000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt

DSPE-2arm PEG 5,000
N-[Carbonyl-2’,3’-Bis(methoxypolyethyleneglycol 5000)]-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt *make-to-order

3-(N-succinimidyloxyglutaryl)aminopropyl, polyethyleneglycol-carbamyl distearoylphosphatidyl-ethanolamine *make-to-order

N-[(3-Maleimide-1-oxopropyl)aminopropyl polyethyleneglycol-carbamyl] distearoylphosphatidyl-ethanolamine *make-to-order

N-(aminopropyl polyethyleneglycol)carbamyl-distearoylphosphatidyl-ethanolamine

DMG-PEG 2,000
1,2-Dimyristoyl-rac-glycerol, methoxypolyethylene Glycol


DMG-PEG 5,000
1,2-Dimyristoyl-rac-glycerol, methoxypolyethylene Glycol *make-to-order

DOG-PEG 2,000
1,2-Dioleoyl-rac-glycerol, methoxypolyethylene Glycol

DOG-PEG 5,000
1,2-Dioleoyl-rac-glycerol, methoxypolyethylene Glycol *make-to-order

DPG-PEG 2,000
1,2-Dipalmitoyl-rac-glycerol, methoxypolyethylene Glycol

DPG-PEG 5,000
1,2-Dipalmitoyl-rac-glycerol, methoxypolyethylene Glycol *make-to-order